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  Indian J Med Microbiol
 

Figure 2:68Ga-prostate-specific membrane antigen positron emission tomography/computed tomography was performed for a 71-year-old male with a history of prostate adenocarcinoma (GS: 4 + 5) underwent prostatectomy 6 years ago. One year after prostatectomy, due to local recurrence, the patient underwent second surgery, external beam radiation therapy and brachytherapy. Due to rising prostate-specific antigen,68Ga-prostate-specific membrane antigen positron-emission tomography/computed tomography was performed for recurrence evaluation. The scan revealed a mid-esophageal mass with esophageal stenosis and highly increased radiotracer uptake, suggesting a second primary cancer with mediastinal lymph nodes metastases. According to the prior studies, increased prostate-specific membrane antigen expression maybe due to significant neovascularization revealed in gastroesophageal cancers[21],[38]

Figure 2:<sup>68</sup>Ga-prostate-specific membrane antigen positron emission tomography/computed tomography was performed for a 71-year-old male with a history of prostate adenocarcinoma (GS: 4 + 5) underwent prostatectomy 6 years ago. One year after prostatectomy, due to local recurrence, the patient underwent second surgery, external beam radiation therapy and brachytherapy. Due to rising prostate-specific antigen,<sup>68</sup>Ga-prostate-specific membrane antigen positron-emission tomography/computed tomography was performed for recurrence evaluation. The scan revealed a mid-esophageal mass with esophageal stenosis and highly increased radiotracer uptake, suggesting a second primary cancer with mediastinal lymph nodes metastases. According to the prior studies, increased prostate-specific membrane antigen expression maybe due to significant neovascularization revealed in gastroesophageal cancers<sup>[21],[38]</sup>