World Journal of Nuclear Medicine

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 19  |  Issue : 4  |  Page : 341--346

Renal cortical transit time as a predictor for pyeloplasty in pediatric patients with unilateral hydronephrosis


Stuart S More1, John Lazarus2, Anita Brink1 
1 Division of Nuclear Medicine, Groote Schuur Hospital and Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa
2 Division of Urology, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa

Correspondence Address:
Dr. Stuart S More
A3.62 Department of Medical Imaging, Division of Nuclear Medicine, Red Cross War Memorial Children's Hospital, Klipfontein Road, Rondebosch, Cape Town 7700
South Africa

Majority of patients with unilateral hydronephrosis (HN) detected on ultrasound do not require pyeloplasty. The measurement of the cortical transit time (CTT) has been demonstrated by several authors to predict the need for patients who may require pyeloplasty. The study aimed to assess if CTT would have predicted a drop in differential renal function (DRF) in patients with unilateral HN on the affected side and to assess whether CTT would differ on the first renogram between those patients who had a pyeloplasty and those who did not have a pyeloplasty. Sixty-eight patients with at least two renograms with unilateral HN with a normal contralateral kidney were observed retrospectively. The CTT was recorded for each kidney. Renograms were processed three times to measure the DRF. The mean of the three DRF measurements was used for analysis. The mean CTT of the left and right hydronephrotic kidneys was 6.0 min and 6.7 min, respectively. The relationship between CTT and DRF as well as CTT and anterior posterior diameter in the first renogram of those patients who did not have a pyeloplasty was statistically significant (P < 0.05). In the 20 patients who had a pyeloplasty, there was a drop of more than 10% in the DRF of three patients. No significant difference was found in CTT or DRF when comparing the group who had surgery against the group who did not have surgery. The current study was unable to demonstrate in our series of patients that CTT can predict a drop in DRF in those patients who would require pyeloplasty.


How to cite this article:
More SS, Lazarus J, Brink A. Renal cortical transit time as a predictor for pyeloplasty in pediatric patients with unilateral hydronephrosis.World J Nucl Med 2020;19:341-346


How to cite this URL:
More SS, Lazarus J, Brink A. Renal cortical transit time as a predictor for pyeloplasty in pediatric patients with unilateral hydronephrosis. World J Nucl Med [serial online] 2020 [cited 2021 Jan 15 ];19:341-346
Available from: http://www.wjnm.org/article.asp?issn=1450-1147;year=2020;volume=19;issue=4;spage=341;epage=346;aulast=More;type=0