World Journal of Nuclear Medicine

CASE REPORT
Year
: 2020  |  Volume : 19  |  Issue : 2  |  Page : 159--161

Neurolymphomatosis – Rare presentation in non-Hodgkin's lymphoma: The role of18F-fluorodeoxyglucose positron-emission tomography and computerized tomography imaging


Nosheen Fatima1, Maseeh Uz Zaman1, Areeba Zaman2, Sidra Uz Zaman3 
1 Department of Radiology, The Aga Khan University Hospital, Karachi, Pakistan
2 Department of Medicine, Civil Hospital Karachi, Karachi, Pakistan
3 Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

Correspondence Address:
Dr. Maseeh Uz Zaman
Department of Radiology, The Aga Khan University Hospital, Karachi
Pakistan

Neurolymphomatosis (NLS) is infiltration of lymphoma cells into the peripheral or cranial nervous system and is a rare manifestation of non-Hodgkin lymphoma (NHL). Nerve biopsy is considered as the gold standard for diagnosis but not a preferred choice, and magnetic resonance imaging has lower reported sensitivity.18F-Fluorodeoxyglucose (18FDG) positron-emission tomography and computerized tomography (PET/CT) has a higher sensitivity for diagnosing and assessing the neurological and nonneurological metabolic tumor volume and response evaluation to therapy. We present the case of a lady, known to have NHL in remission. She presented with a short history of severe pain and weakness of the right lower limb. Baseline and interim18FDG PET/CT played a crucial role in diagnosing and assessing the extent of NLS and nonneurological disease burden and also in evaluation of response to treatment.


How to cite this article:
Fatima N, Zaman MU, Zaman A, Zaman SU. Neurolymphomatosis – Rare presentation in non-Hodgkin's lymphoma: The role of18F-fluorodeoxyglucose positron-emission tomography and computerized tomography imaging.World J Nucl Med 2020;19:159-161


How to cite this URL:
Fatima N, Zaman MU, Zaman A, Zaman SU. Neurolymphomatosis – Rare presentation in non-Hodgkin's lymphoma: The role of18F-fluorodeoxyglucose positron-emission tomography and computerized tomography imaging. World J Nucl Med [serial online] 2020 [cited 2021 Aug 5 ];19:159-161
Available from: http://www.wjnm.org/article.asp?issn=1450-1147;year=2020;volume=19;issue=2;spage=159;epage=161;aulast=Fatima;type=0