World Journal of Nuclear Medicine

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 13  |  Issue : 1  |  Page : 50--55

Comparative Study of Radionuclide Uptake Levels between Primary and Metastatic Bone Tumors


Yigbedeck Yolande Ebele Huguette1, Kyere Augustine Kwame1, Wilson Isaac Kojo2, Hasford Francis3, Sosu Edem Kwabla3, Ankrah Alfred Otoe2 
1 Department of Medical Physics, School of Nuclear and Allied Sciences, University of Ghana, Accra, Ghana
2 Department of Nuclear Medicine, National Centre for Radiotherapy and Nuclear Medicine, Korle-Bu Teaching Hospital, Accra, Ghana
3 Department of Medical Physics, School of Nuclear and Allied Sciences, University of Ghana; Medical Radiation Physics Centre, Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, Accra, Ghana

Correspondence Address:
Hasford Francis
Medical Radiation Physics Centre, Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, P.O. Box LG 80, Legon, Accra
Ghana

Study on 95 patients to compare radionuclide uptake levels in patients undergoing bone scintigraphy at a Nuclear Medicine Unit has been performed quantitatively using Image J software. Patients were administered with activity ranging from 0.555 to 1.110 MBq depending on their body weight, and their whole-body bone scans obtained with an installed e.cam single-photon emission computed tomography system. Matrix size of 256 × 1024 was used in acquiring the scintigrams. Quantitative analyses performed with installed Image J software revealed higher radionuclide uptake levels in metastatic tumors compared with primary tumors for all selected skeletal parts. Average normalized count of activity in metastatic tumors was 37.117 ± 27.740 cts/mm 2 /MBq and its corresponding uptake in primary tumors was 23.035 ± 19.542 cts/mm 2 /MBq. The relative higher uptake in metastatic tumors over primary tumors could be attributed to higher osteoblastic activity and blood flow in metastatic tumors.


How to cite this article:
Huguette YY, Kwame KA, Kojo WI, Francis H, Kwabla SE, Otoe AA. Comparative Study of Radionuclide Uptake Levels between Primary and Metastatic Bone Tumors.World J Nucl Med 2014;13:50-55


How to cite this URL:
Huguette YY, Kwame KA, Kojo WI, Francis H, Kwabla SE, Otoe AA. Comparative Study of Radionuclide Uptake Levels between Primary and Metastatic Bone Tumors. World J Nucl Med [serial online] 2014 [cited 2020 Oct 29 ];13:50-55
Available from: http://www.wjnm.org/article.asp?issn=1450-1147;year=2014;volume=13;issue=1;spage=50;epage=55;aulast=Huguette;type=0