Monte Carlo simulation and performance assessment of GE Discovery 690 VCT positron emission tomography/computed tomography scanner

Elham Kashian; Hadi Taleshi Ahangari; Vahab Dehlaghi; Karim Khoshgard; Pardis Ghafarian; Raheb Ghorbani

doi:10.4103/wjnm.WJNM_4_20

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ORIGINAL ARTICLE

Year : 2020 | Volume : 19 | Issue : 4 | Page : 366-375

Monte Carlo simulation and performance assessment of GE Discovery 690 VCT positron emission tomography/computed tomography scanner

Elham Kashian¹, Hadi Taleshi Ahangari², Vahab Dehlaghi¹, Karim Khoshgard³, Pardis Ghafarian⁴, Raheb Ghorbani⁵
¹ Department of Biomedical Engineering and Medical Physics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
² Department of Medical Physics, Faculty of medicine, Semnan University of Medical Sciences, Semnan, Iran
³ Department of Medical Physics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
⁴ Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD); PET/CT and Cyclotron Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
⁵ Department of Social Medicine, Faculty of medicine, Semnan University of Medical Sciences, Semnan, Iran

Correspondence Address:
Dr. Hadi Taleshi Ahangari
Department of Medical Physics, Faculty of Medicine, Semnan University of Medical Sciences, Semnan
Iran
Dr. Vahab Dehlaghi
Department of Biomedical Engineering, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah
Iran

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DOI: 10.4103/wjnm.WJNM_4_20

The aim of this study is to simulate GE Discovery 690 VCT positron emission tomography/computed tomography (PET/CT) scanner using Geant4 Application for Tomographic Emission (GATE) simulation package (version 8). Then, we assess the performance of scanner by comparing measured and simulated parameter results. Detection system and geometry of PET scanner that consists of 13,824 LYSO crystals designed in 256 blocks and 24 ring detectors were modeled. In order to achieve a precise model, we verified scanner model. Validation was based on a comparison between simulation data and experimental results obtained with this scanner in the same situation. Parameters used for validation were sensitivity, spatial resolution, and contrast. Image quality assessment was done based on comparing the contrast recovery coefficient (CRC) of simulated and measured images. The findings demonstrate that the mean difference between simulated and measured sensitivity is <7%. The simulated spatial resolution agreed to within <5.5% of the measured values. Contrast results had a slight divergence within the range below 4%. The image quality validation study demonstrated an acceptable agreement in CRC for 8:1 and 2:1 source-to-background activity ratio. Validated performance parameters showed good agreement between experimental data and simulated results and demonstrated that GATE is a valid simulation tool for simulating this scanner model. The simulated model of this scanner can be used for future studies regarding optimization of image reconstruction algorithms and emission acquisition protocols.

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