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Year : 2017  |  Volume : 16  |  Issue : 1  |  Page : 68-70

Kikuchi-Fujimoto disease with 18f-fludeoxyglucose uptake in cervical lymph nodes on dual-time-point imaging positron emission tomography/computed tomography mimicking malignant disease

1 Division of Oral and Maxillofacial Surgery, School of Medicine, Tokai University, Tokyo; Division of Oral and Maxillofacial Surgery, Oiso Hospital, Japan
2 Division of Oral and Maxillofacial Surgery, School of Medicine, Tokai University, Tokyo, Japan

Correspondence Address:
Ken-ichi Aoyama
143 Shimokasuya, Isehara, Kanagawa - 259-1193
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DOI: 10.4103/1450-1147.174712

PMID: 28217024

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Kikuchi-Fujimoto disease (KFD) is a benign but self-limiting disorder. However, KFD is often misdiagnosed as a malignant disease. Although 18F-fludeoxyglucose (FDG) uptake on dual-time-point imaging (DTPI) positron emission tomography (PET)/computed tomography (CT) is useful in distinguishing malignant from benign disease, the latter sometimes mimics malignancy on DTPI PET/CT, resulting in a misdiagnosis. Here, we describe the case of a 30-year-old woman who complained of cervical lymphadenopathy. PET showed increased FDG uptake in multiple lymph nodes, with a maximum standardized uptake value (SUVmax) of 19.0 in the early phase to 21.8 in the late phase. A biopsy was performed, and pathological examination revealed KFD. KFD with FDG uptake in lymph nodes on DTPI PET/CT is rare and difficult to be distinguished from a malignant disease.

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