| CASE REPORT |
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| Year : 2016 | Volume
: 15
| Issue : 3 | Page : 212-214 |
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Radiation-induced leiomyosarcoma of the oral cavity: A rare occurrence detected on 18F-FDG PET/CT
Fouzia Siraj1, Varsha Dalal1, Manveen Kaur1, Kapil Suri2
1 Department of Pathology, National Institute of Pathology, Indian Council of Medical Research, New Delhi, India
2 Department of Radiotherapy, Safdarjung Hospital, New Delhi, India
Correspondence Address:
Varsha Dalal
National Institute of Pathology, Indian Council of Medical Research, Safdarjung Hospital Campus, New Delhi - 110 029
India
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DOI: 10.4103/1450-1147.172306 PMID: 27651746 
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Radiation-induced sarcomas (RIS) or postirradiation sarcomas have been reported as a rare long-term complication of radiation therapy (RT). The survival benefit offered by radiotherapy has been masked by an increase in the incidence of these sarcomas, thus making radiotherapy a double-edged sword. RIS generally develop with a mean latency period of 10-15 years and encompass different histological types. We report a case of oral leiomyosarcoma with a rather short latency period of 4 years after the radiotherapy of the prior oral squamous cell carcinoma (OSCC) detected on fluorine-18 (18F)-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT). The rarity of occurrence of leiomyosarcoma in the oral cavity is also highlighted. |
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