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Year : 2016  |  Volume : 15  |  Issue : 3  |  Page : 209-211

An extremely rare intersection: Neurolymphomatosis in a patient with burkitt lymphoma detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography

1 Department of Nuclear Medicine, Afyon Kocatepe University, Afyon, Turkey
2 Department of Nuclear Medicine, Gulhane Military Medical Academy, Ankara, Turkey
3 Department of Radiology, Gulhane Military Medical Academy, Ankara, Turkey

Correspondence Address:
Ali Ozan Oner
Department of Nuclear Medicine, School of Medicine, Afyon Kocatepe University, Afyon
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1450-1147.172304

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Neurolymphomatosis (NL) is a rarely seen neurologic involvement of the systematic lymphoma. Its diagnosis is challenging, and requires biopsy. In cases where biopsy is not appropriate, 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) may aid in diagnosis. Here, we present a 54-year old male patient diagnosed with Burkitt lymphoma who underwent FDG-PET/CT in order to evaluate the treatment response after chemotherapy and radiotherapy. On viewing PET/CT images of the patient who complained of pain and weakness in his upper extremities after therapy, linear FDG uptake was observed in bilateral cervical 5 (C5), left cervical 6 (C6), bilateral cervical 7 (C7), and right lumbar 4 (L4) nerve roots. Magnetic resonance imaging (MRI) revealed dilation and thickening of nerve roots consisted with FDG uptake observed on PET/CT images. Since biopsy was not performed, histopathological diagnosis could not be established. However, overlapping of clinical, PET/CT, and MRI findings strongly suggested the presence of NL. As is the case of this patient, in cases with non-Hodgkin lymphoma, a combined evaluation of FDG-PET/CT and MRI modalities aid in the establishment of the diagnosis of NL.

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