| CASE REPORT |
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| Year : 2016 | Volume
: 15
| Issue : 1 | Page : 50-52 |
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The complimentary role of Methoxy-Isobutyl-Isonitrile and hand-held gamma probe in adamantinoma
Masha Maharaj1, Nisaar Korowlay2, Ellmann Prof 2
1 Department of Nuclear Medicine, Umhlanga Molecular Imaging and Therapy, Centre of Excellence, Umhlanga, South Africa
2 Department of Medical Imaging and Clinical Oncology, Stellenbosch University, and Tygerberg Hospital, South Africa
Correspondence Address:
Masha Maharaj
Department of Nuclear Medicine, Umhlanga Molecular Imaging and Therapy, Centre of Excellence, Umhlanga, 4319
South Africa
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DOI: 10.4103/1450-1147.167600 PMID: 26912979 
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Adamantinoma is a rare locally aggressive osteolytic tumor that is found 90% of the time in the diaphysis of the tibia with the remaining lesions found in the fibula and long tubular bones. A case of adamantinoma of the tibia is presented. The added value of nuclear medicine investigations in the workup of this patient is described. A three-phase whole body 99mTc-methylene diphosphonate bone and a whole body 99mTc-methoxy-isobutyl-isonitrile scans were complimentary in the demarcation of viable bone tumor and the assessment of the remainder of the bone and soft tissue to exclude other sites. Intra-operative assistance with a hand-held gamma probe, guided the biopsy of the most metabolically active tumor tissue. Histology revealed a biphasic tumor composed of epithelial and fibrous components, in keeping with an adamantinoma. |
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