Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 1230  
Year : 2014  |  Volume : 13  |  Issue : 1  |  Page : 16-21

Lacrimal Outflow Mechanisms and the Role of Scintigraphy: Current Trends

1 Department of Ophthalmology, University Hospital of Heraklion, Heraklion, Crete, Greece
2 Department of Nuclear Medicine, University Hospital of Alexandroupolis, Greece
3 Department of Ophthalmology, University Hospital of Alexandroupolis, Greece

Correspondence Address:
Dr. Efstathios T Detorakis
Department of Ophthalmology, University Hospital of Heraklion, 71110 Heraklion, Crete
Login to access the Email id

DOI: 10.4103/1450-1147.138569

PMID: 25191107

Rights and Permissions

Lacrimal outflow can be compromised by anatomical obstructions or stenoses (nonfunctional epiphora) or by defective lacrimal "pump" function (functional epiphora). Although classic imaging modalities, such as X-ray dacryocystography, computed tomography, or magnetic resonance imaging can effectively evaluate the former, their success is much less in the evaluation of the latter. This is largely due to the fact that forced diagnostic injection of fluid into the canalicular system can overcome partial obstruction sites. On the other hand, lacrimal scintigraphy mimicks "physiological" lacrimal outflow, being performed under pressure gradients present in everyday life. This is why it is considered more suitable for the study of functional epiphora. Furthermore, quantitative lacrimal scintigraphy (with time-activity curves) enables the accurate measurement of lacrimal clearance from the conjunctival fornices and may be used to study the physiology of the lacrimal "pump." Data obtained from the scintigraphic study of lacrimal outflow may be used to design more effective procedures in the management of functional and nonfunctional epiphora. This is a review article, based on a literature search with emphasis on recent publications and on those supporting interdisciplinary cooperation between ophthalmology and nuclear medicine.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded662    
    Comments [Add]    
    Cited by others 16    

Recommend this journal