World Journal of Nuclear Medicine

LETTER TO EDITOR
Year
: 2015  |  Volume : 14  |  Issue : 1  |  Page : 71-

Accuracy of Positron Emission Tomography-Computed Tomography in Bone Marrow Involvement Lymphoma


Demet Cekdemir1, Serdar Olt2, Hasan Ergenc3, Ali Tamer3,  
1 Department of Hematology, Kocaeli Acibadem Hospital, Kocaeli, Turkey
2 Department of Internal Medicine, Bitlis Mutki State Hospital, Bitlis, Turkey
3 Department of Internal Medicine, Sakarya University Medical Faculty, Sakarya, Turkey

Correspondence Address:
Serdar Olt
Department of Internal Medicine, Bitlis Mutki State Hospital, Bitlis
Turkey




How to cite this article:
Cekdemir D, Olt S, Ergenc H, Tamer A. Accuracy of Positron Emission Tomography-Computed Tomography in Bone Marrow Involvement Lymphoma.World J Nucl Med 2015;14:71-71


How to cite this URL:
Cekdemir D, Olt S, Ergenc H, Tamer A. Accuracy of Positron Emission Tomography-Computed Tomography in Bone Marrow Involvement Lymphoma. World J Nucl Med [serial online] 2015 [cited 2020 Feb 26 ];14:71-71
Available from: http://www.wjnm.org/text.asp?2015/14/1/71/150564


Full Text

Dear Editor,

Spread of lymphoma should be determined before treatment modality. Bone marrow involvement is an important part of staging of lymphoma. Recently the most commonly used imaging modality in lymphoma is positron emission tomography-computed tomography (PET-CT). Glucose metabolic activity is high in most lymphoma and we can evaluate spread of lymphoma with PET-CT because of its high uptake of fluorodeoxyglucose. [1] Nowadays bone marrow biopsy and PET-CT is used routinely in order to staging of lymphoma. [2]

We aimed to test PET-CT in bone marrow involvement lymphoma. We included 15 lymphoma patients in our study, and all patients underwent bone marrow biopsy. PET-CT was applied all patients. 10 out of 15 (66.6%) patients showed positive PET-CT results. Positive pathological biopsy material were found in eight out of 15 patients (53.3%). 40% of PET-CT findings proved true positive, 26.6% were found to be false positive. 20% proved true negative and 13.3% false negative. This results in a specificity of 42.8% and a sensitivity of 75%.

[INLINE:1]

Here we wanted to emphasis our experience of PET-CT in lymphoma.

References

1Chavdarova LI, Tzonevska AD, Piperkova EN. Discrepancies and priorities in staging and restaging malignant lymphoma by SPET, SPET/CT, PET/CT and PET/MRI. Hell J Nucl Med 2013;16:223-9.
2Jhanwar YS, Straus DJ. The role of PET in lymphoma. J Nucl Med 2006;47:1326-34.