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CASE REPORT
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Vas deferens infiltration by prostate cancer on prostate-specific membrane antigen-targeted 18F-DCFPyL positron emission tomography/computed tomography: A unique visual pattern


1 The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China
2 Department of Oncology, The Sidney Kimmell Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
3 The Russell H. Morgan Department of Radiology and Radiological Science; Department of Oncology, The Sidney Kimmell Comprehensive Cancer Center; Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
4 Department of Oncology, The Sidney Kimmell Comprehensive Cancer Center; Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA
5 The Russell H. Morgan Department of Radiology and Radiological Science; Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Correspondence Address:
Steven P Rowe,
The Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine 600 N. Wolfe St., Baltimore, MD 21287
USA
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/wjnm.WJNM_50_18

New radiotracers for positron emission tomography imaging that target prostate-specific membrane antigen (PSMA) have emerged as important clinical tools for imaging prostate cancer (PCa). PSMA-targeted radiotracers have demonstrated high sensitivity and high specificity for detecting sites of PCa and are demonstrably superior to conventional imaging modalities such as computed tomography and bone scan. Vas deferens invasion is a rarely encountered poor prognostic feature of PCa. In this case report, we describe a novel pattern of radiotracer uptake in a patient with PCa imaged with PSMA-targeted 18F-DCFPyL positron emission tomography/computed tomography that is consistent with diffuse vas deferens involvement.


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    -  Yin Y
    -  Paller CJ
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