Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 443  
CASE REPORT
Year : 2020  |  Volume : 19  |  Issue : 1  |  Page : 61-64

Failure of iodine uptake in microscopic pulmonary metastases after recombinant human thyroid-stimulating hormone stimulation


1 Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
2 Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Francisco, CA, USA
3 Department of Endocrinology, Southern California Permanente Medical Group, Fontana, CA, USA

Correspondence Address:
Dr. Courtney Lawhn-Heath
Department of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue, M-391, San Francisco, CA
USA
Login to access the Email id


DOI: 10.4103/wjnm.WJNM_29_19

Rights and Permissions

Elevated thyroid stimulating hormone (TSH) is required when preparing for radioactive iodine therapy in patients with differentiated thyroid cancer. Recombinant human TSH (rhTSH: Thyrogen; Genzyme Corporation, Cambridge, MA) avoids hypothyroidism and has been commonly used in place of thyroid hormone withdrawal (THW) in this process. We describe a 31-year-old woman with sclerosing variant of papillary thyroid cancer with multiple lymph node metastases and elevated postoperative thyroglobulin suggesting the presence of distant metastases, who was found to have miliary pulmonary metastases on the posttherapy I-131 scan after THW, but not visible on the post therapy scan after rhTSH preparation.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed363    
    Printed7    
    Emailed0    
    PDF Downloaded66    
    Comments [Add]    

Recommend this journal