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CASE REPORT
Year : 2016  |  Volume : 15  |  Issue : 3  |  Page : 212-214

Radiation-induced leiomyosarcoma of the oral cavity: A rare occurrence detected on 18F-FDG PET/CT


1 Department of Pathology, National Institute of Pathology, Indian Council of Medical Research, New Delhi, India
2 Department of Radiotherapy, Safdarjung Hospital, New Delhi, India

Correspondence Address:
Varsha Dalal
National Institute of Pathology, Indian Council of Medical Research, Safdarjung Hospital Campus, New Delhi - 110 029
India
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DOI: 10.4103/1450-1147.172306

PMID: 27651746

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Radiation-induced sarcomas (RIS) or postirradiation sarcomas have been reported as a rare long-term complication of radiation therapy (RT). The survival benefit offered by radiotherapy has been masked by an increase in the incidence of these sarcomas, thus making radiotherapy a double-edged sword. RIS generally develop with a mean latency period of 10-15 years and encompass different histological types. We report a case of oral leiomyosarcoma with a rather short latency period of 4 years after the radiotherapy of the prior oral squamous cell carcinoma (OSCC) detected on fluorine-18 (18F)-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT). The rarity of occurrence of leiomyosarcoma in the oral cavity is also highlighted.


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