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REVIEW ARTICLE
Year : 2016  |  Volume : 15  |  Issue : 1  |  Page : 3-6

Comparison of [15O] H2O positron emission tomography and functional magnetic resonance imaging in activation studies


1 Division of Nuclear Medicine, National Center for Global Health and Medicine; Division of Nuclear Medicine, Keio University, Tokyo, Japan
2 Division of Nuclear Medicine, Keio University, Tokyo, Japan
3 Department of Radiology, School of Medicine, Keio University, Tokyo, Japan

Correspondence Address:
Masashi Kameyama
Division of Nuclear Medicine, National Center for Global Health and Medicine, 1-2-1 Toyama, Shinjuku.ku, Tokyo - 160 - 8655; Division of Nuclear Medicine, Department of Radiology, School of Medicine, Keio University, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582
Japan
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DOI: 10.4103/1450-1147.172139

PMID: 26912971

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[15O] H2O positron emission tomography (PET) has long been out of use in activation studies on the brain. Indeed, it is true that blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has better spatial resolution and temporal resolution than PET, as well as no radiation exposure. However, PET and fMRI differ in their scope. Compared to fMRI, [15O] H2O PET offers advantages such as being quantifiable, less deteriorated by movement, and allowing for longitudinal studies. This article aimed to reassess the merits of PET in this context.


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