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REVIEW ARTICLE
Year : 2015  |  Volume : 14  |  Issue : 2  |  Page : 75-80

Advances in SPECT for Optimizing the Liver Tumors Radioembolization Using Yttrium-90 Microspheres


1 Department of Medical Physics, Nuclear Medicine Unit, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Radiology, Nuclear Medicine Unit, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

Correspondence Address:
Jalil Pirayesh Islamian
Department of Medical Physics, School of Medicine, Tabriz University of Medical Sciences, Attar Neyshapouri Street, Azadi Avenue, Tabriz 5166614766
Iran
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DOI: 10.4103/1450-1147.157120

PMID: 26097416

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Radioembolization (RE) with Yttrium-90 ( 90 Y) microspheres is an effective treatment for unresectable liver tumors. The activity of the microspheres to be administered should be calculated based on the type of microspheres. Technetium-99m macroaggregated albumin ( 99m Tc-MAA) single photon emission computed tomography/computed tomography (SPECT/CT) is a reliable assessment before RE to ensure the safe delivery of microspheres into the target. 90 Y bremsstrahlung SPECT imaging as a posttherapeutic assessment approach enables the reliable determination of absorbed dose, which is indispensable for the verification of treatment efficacy. This article intends to provide a review of the methods of optimizing 90 Y bremsstrahlung SPECT imaging to improve the treatment efficacy of liver tumor RE using 90 Y microspheres.


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