Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
  Home Print this page Email this page Small font sizeDefault font sizeIncrease font size Users Online: 712  
ORIGINAL ARTICLE
Year : 2014  |  Volume : 13  |  Issue : 2  |  Page : 88-93

Uptake of 18 F-fluoro-2-deoxyglucose in the Healthy Testes of Young Men as Assessed by Positron Emission Tomography/Computed Tomography; Including the Inter- and Intra-observer Variation


Department of Surgery, Medical Centre, Alkmaar, the Netherlands

Correspondence Address:
A Meij-de Vries
Medical Centre, Alkmaar
the Netherlands
Login to access the Email id


DOI: 10.4103/1450-1147.139137

PMID: 25191122

Rights and Permissions

Knowledge of the physiological testicular accumulation of 18 F-fluoro-2-deoxyglucose (FDG) is essential in order to discriminate between normal and pathological findings. In this study, the 18 F-FDG-uptake in healthy testes of young men was assessed using positron emission tomography/computed tomography (PET/CT)-scans. A total of 40 testes of 20 men with a mean age of 26.5 ± 3.9 years were evaluated. 18 F-FDG-uptake was expressed as the standardized uptake value (SUV). Testicular volume was measured on CT and PET. All scans were assessed by three researchers, one of whom assessed every scan twice. Laterality indices and inter- and intra-observer variation were evaluated. Correlation between the SUV max and SUV peak , between SUV mean and SUV peak and between age and SUV peak were assessed. Testes showed an average SUV max of 3.42 ± 0.61 , SUV peak of 3.06 ± 0.54 and SUV mean of 2.44 ± 0.44. The average testicular volume on CT was 23.0 ± 6.4 ml, whereas on PET it was 18.0 ± 5.1 ml. Laterality indices were calculated of 0.077 ± 0.065 (SUV max ), 0.074 ± 0.066 (SUV peak ), 0.072 ± 0.063 (SUV mean ), 0.245 ± 0.259 (CT), and 0.200 ± 0.188 (PET), respectively. Inter- and intra-observer reliability were found to be perfect for the SUVs (intraclass correlation coefficient [ICC] 0.992-1.0), but poor for testicular volumes (ICC 0.854-0.902). Testicular 18 F-FDG uptake in young men can be measured accurately on PET/CT and shows high symmetry. Consequently, 18 F-FDG PET/CT has the potential to become a useful instrument in the evaluation of the functioning of the individual testis.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2209    
    Printed58    
    Emailed1    
    PDF Downloaded233    
    Comments [Add]    
    Cited by others 1    

Recommend this journal