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CASE REPORT
Year : 2013  |  Volume : 12  |  Issue : 1  |  Page : 48-50

Excessive Hepatic Arterial-portal Venous Shunting May Predict Failure of Microparticle Localization in Hepatocellular Carcinomas


Department of Nuclear Medicine and PET, Singapore General Hospital, Outram, Singapore

Correspondence Address:
Wanying Xie
Department of Nuclear Medicine and PET, Singapore General Hospital, Outram Road, Singapore 169608
Singapore
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DOI: 10.4103/1450-1147.113966

PMID: 23961258

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Locoregional treatment of hepatocellular carcinomas using yttrium-90 (Y-90) microspheres is an emerging modality, and involves the administration of such radioactive particles directly into the hepatic arterial vasculature. We present the case of a 58-year-old gentleman undergoing evaluation for Y-90 microsphere therapy for hepatocellular carcinoma, in which our findings suggest that significant hepatic arterial portal venous shunting detected during the angiogram maybe a predictor of poor localization of microspheres in the turmor, and that centers that utilize body surface area (BSA) approaches for dosimetry should take note of such findings.


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