| DOSIMETRY |
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| Year : 2011 | Volume
: 10
| Issue : 2 | Page : 122-138 |
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Dosimetric Considerations in Radioimmunotherapy and Systemic Radionuclide Therapies: A Review
Kelvin S.H Loke1, Ajit K Padhy1, David C.E Ng1, Anthony S.W Goh1, Chaitanya Divgi2
1 Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore
2 Department of Radiology, Columbia University, USA
Correspondence Address:
Kelvin S.H Loke
Consultant, Department of Nuclear Medicine and PET, Singapore General Hospital
Singapore
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DOI: 10.4103/1450-1147.89780 PMID: 22144871 
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Radiopharmaceutical therapy, once touted as the "magic bullet" in radiation oncology, is increasingly being used in the treatment of a variety of malignancies; albeit in later disease stages. With ever-increasing public and medical awareness of radiation effects, radiation dosimetry is becoming more important. Dosimetry allows administration of the maximum tolerated radiation dose to the tumor/organ to be treated but limiting radiation to critical organs. Traditional tumor dosimetry involved acquiring pretherapy planar scans and plasma estimates with a diagnostic dose of intended radiopharmaceuticals. New advancements in single photon emission computed tomography and positron emission tomography systems allow semi-quantitative measurements of radiation dosimetry thus allowing treatments tailored to each individual patient. |
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